Impact of Global Warming and Climate Change in Allergic Diseases
Global warming and climate change affect the prevalence and severity of allergies and allergic diseases.
Mite Growth Media without Animal Components – Mites for The Production of Allergenic Extracts and The Impact of Medical Regulatory Agencies
Allergenic extracts are used to diagnose and treat allergic diseases. Many types of allergenic extracts are available, including those from mites. Different mite species are used to produce allergenic extracts. The most common mite species raised for this purpose include Dermatophagoides pteronyssinus and Dermatophagoides farinae, which are grown on media rich in nutrients until the […]
The Relevance of Pollen and Fungal Spores in Allergic Diseases
Pollen and fungal spores are associated with seasonal and perennial allergies. However, most scientific literature thus far suggests that pollen allergy is more clinically relevant than fungal allergy. Several environmental and biological factors and the difficulty in producing reliable fungal extracts account for this. Biodiversity, taxonomy, and meteorology are responsible for the types and levels […]
Allergenic Materials to Produce Extracts – Natural or Recombinant Allergens
Allergenic materials are used to prepare allergen extracts to diagnose and treat allergic patients. Natural allergenic materials have been used for this purpose for many years. It is often difficult to obtain enough sufficient quantities of natural allergenic materials. In addition, the safety of those allergenic materials is questioned, particularly in Europe, where medical regulatory […]
Fungal Allergenic Extracts
A large number of fungal allergenic extracts for diagnosis and treatment of allergic diseases are available on the market. This can be confusing for the allergist/immunologist to properly select the most clinically relevant fungal allergenic extracts. While the proper selection of the appropriate fungal allergenic extracts derived from particular genera and/or species is critical, other […]
Dog Allergenic Extracts
Dog allergenic extracts are used to diagnose and treat allergic diseases. Mammalian allergens are present in a variety of sources, and different raw materials are used to produce dog allergenic extracts extracts. Those materials include dog dander, hair, epithelium, pelt, skin scrapings, and hides. However, dog dander is the most commonly used product. Because most […]
Pollen Allergenic Extracts
Pollen is a unique raw material because it is exposed to the outdoor environment before and during collection. Therefore, pollen can be potentially impacted by moisture and airborne components present outdoors. They include both ubiquitous biological and chemical environmental pollutants. The potential impact of chemical contaminants in pollen is not discussed here. Proper pollen collection […]
Allergenic Extracts on the Market
A large number of allergenic extracts for diagnosis and/or treatment of allergies are available on the market. However, the safety and efficacy of many of them are controversial. In 2004, the Food and Drug Administration (FDA) Center for Biologics Evaluations and Research (CBER), which regulates allergenic products, created a committee to review scientific data about […]
Storage of Allergenic Raw Materials
Environmental factors are responsible for the deterioration of the allergenic raw materials used to manufacture allergenic extracts. Among these factors, moisture content and storage temperature of the materials play a combined role, responsible for the allergenic stability of raw materials. The proper storage of allergenic raw materials is critical to guarantee a particular shelf-life. We […]
Production of Allergenic Extracts
Introduction: Allergen extracts are biological products used to diagnose and treat allergic diseases. Allergy diagnosis is performed by a careful review of the patient’s medical history, often followed by in vivo and/or in vitro testing, which involve the use of allergen extracts. Allergen avoidance should be the first measure to prevent allergies. However, this approximation […]